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1. Preheat oven to 350 degrees and line pans with cupcake liners.
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2. Sift cake mix into a large bowl to remove any lumps and add eggs, oil, milk, sour cream and vanilla extract. Stir until smooth.
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3. Stir in Reese's Pieces and fill cupcake liners 3/4 full and bake for 15-20 minutes or until an inserted knife comes out clean.
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4. Let cool.
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5. Peanut Butter Frosting: Beat butter and peanut butter until smooth. Add vanilla extract, milk and 1 cup powdered sugar. Beat again. Slowly add in more powdered sugar until you reach your desired consistency. Add more milk if frosting becomes too thick.
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6. Peanut Butter Chocolate Ganache: In a microwave safe bowl, melt chocolate chips and peanut butter together and stir until smooth.
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7. Pipe buttercream onto cooled cupcakes, drizzle over ganache (I made a mini piping bag with a plastic sandwich bag and snipped off the tip) then top with Reese's Pieces.